Pam Singh, MSc, CRA, Research Coordinator for Dr. N. A. Leyland, Department of Obstetrics and Gynecology, McMaster University Medical Centre. She has been working at McMaster in research for the last 22 years. First 10 years in basic research and last 12 years in clinical research. Presently the studies conducted by Dr. N. A. Leyland in 2F clinic at McMaster University Medical Centre are listed below:

Randomized control trials for Fibroids:

We are conducting a clinical research study where we are testing four doses of a new drug and a placebo against symptoms caused by uterine fibroids
The primary purpose of the study is to examine the bleeding intensity in women using this new study drug over 12 weeks.
We are looking for women who are:

• 18-50 years old
• Generally healthy
• Not pregnant or breast feeding
• With Uterine Fibroids
• With heavy menstrual bleeding
• Who would accept assignment to either treatment by chance

If you are interested in learning more about the study or have questions, please contact us via phone or email: Pam Singh, e-mail: [email protected] , Tel: (905) 525-9140, Ext. 21334.

Randomized control trials for Endometriosis:

Do you suffer from pelvic pain related to endometriosis?
Are you interested in participation in a clinical trial which investigates a novel treatment option for endometriosis-related pelvic pain?
We are looking for women who suffer from endometriosis pain and would like to participate in a global Clinical Endometriosis Trial.
The purpose of the trial is to investigate different dose combinations of the study drug applied by an intravaginal ring for the treatment of endometriosis pain.

You may be suitable for the trial if the following apply to you:

• You are at least 18 years of age, but have not yet reached menopause
• Endometriosis has been confirmed within 10 years by laparoscopy or laparotomy
• You suffer from endometriosis related pelvic pain
• You are generally healthy

Participation in this study will be approximately five to six months and during that time you will visit the study center 7 times. The study drug and all study related examinations, for example gynecological examinations and ultrasound, are free of charge. If you are interested in learning more about the study or have questions, please contact us via phone or email: Pam Singh, e-mail: [email protected] , Tel: (905) 525-9140, Ext. 21334.

Identification of a Novel Diagnostic Marker for Endometriosis:

Are you interested in participating in a research study conducted by Dr. Foster and Dr. Leyland, who are looking to identify a novel marker for endometriosis? The study is designed to determine the usefulness of a novel marker for the diagnosis of endometriosis. We are looking for women who will be undergoing a pelvic laparoscopy surgery who have endometriosis and some who do not have endometriosis to participate in this study. The samples needed for this study can be collected during your surgery, which is a small piece of endometrium and this is collected for analysis in the laboratory. Prior to the surgery, you will asked for a blood & urine sample. We will also conduct a questionnaire concerning your gynecological history. There is no more added risk to you than your surgery.
If you are interested in participating or learning more about the study or have questions, please contact us via phone or email: Pam Singh, e-mail: [email protected], Tel: (905) 525-9140, Ext. 21334.